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The effect exerted by one atom of the toxic metal must thus be able to yield a multiplicative effect, such as that corresponding to the inhibition or inactivation of key enzymes that contain thiol groups as part of functional or regulatory mechanism

One of these is a GSH analogue of cyclophosphamide that was shown to enhance toxicity selectively via GST activation in both cell and animal models (Kauvar, 1996)

The Certificate of Analysis provides batch-specific analytical data and quality control information relating to the tested material